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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCG
All Species:
13.94
Human Site:
Y377
Identified Species:
27.88
UniProt:
P05129
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05129
NP_002730.1
697
78448
Y377
R
R
G
S
D
E
L
Y
A
I
K
I
L
K
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116809
695
78118
Y375
R
R
G
S
D
E
L
Y
A
I
K
I
L
K
K
Dog
Lupus familis
XP_541432
673
75218
R377
D
C
T
L
V
E
K
R
V
L
A
L
G
G
R
Cat
Felis silvestris
Mouse
Mus musculus
P20444
672
76833
Q377
L
K
K
D
V
V
I
Q
D
D
D
V
E
C
T
Rat
Rattus norvegicus
P63319
697
78339
Y377
R
R
G
S
D
E
L
Y
A
I
K
I
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510097
675
76844
V378
K
I
L
K
K
D
V
V
I
Q
D
D
D
V
E
Chicken
Gallus gallus
NP_001012822
674
76827
V377
K
I
L
K
K
D
V
V
I
Q
D
D
D
V
E
Frog
Xenopus laevis
Q7LZQ8
671
76506
V374
I
K
I
L
K
K
D
V
V
I
Q
D
D
D
V
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
I376
I
L
K
K
D
V
V
I
Q
D
D
D
V
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05130
679
77676
T395
Q
D
D
D
V
E
C
T
M
I
E
K
R
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90980
682
77982
K380
L
F
A
I
K
V
L
K
K
D
V
I
I
Q
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Y843
T
K
K
S
R
K
L
Y
A
I
K
V
L
K
K
Conservation
Percent
Protein Identity:
100
N.A.
95.5
91.2
N.A.
68.5
99
N.A.
69.8
69.7
66.7
68.1
N.A.
62.1
N.A.
60.6
N.A.
Protein Similarity:
100
N.A.
96.8
92.4
N.A.
81
99.5
N.A.
82.3
81.4
79
80.6
N.A.
75.1
N.A.
74.6
N.A.
P-Site Identity:
100
N.A.
100
6.6
N.A.
0
100
N.A.
0
0
6.6
6.6
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
100
26.6
N.A.
20
100
N.A.
26.6
26.6
26.6
26.6
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
25.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
38
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
34
0
9
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
9
0
0
0
0
0
0
9
9
% C
% Asp:
9
9
9
17
34
17
9
0
9
25
34
34
25
9
9
% D
% Glu:
0
0
0
0
0
42
0
0
0
0
9
0
9
9
17
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
25
0
0
0
0
0
0
0
0
0
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
17
9
9
0
0
9
9
17
50
0
34
9
0
0
% I
% Lys:
17
25
25
25
34
17
9
9
9
0
34
9
0
34
34
% K
% Leu:
17
9
17
17
0
0
42
0
0
9
0
9
34
0
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
9
9
17
9
0
0
9
0
% Q
% Arg:
25
25
0
0
9
0
0
9
0
0
0
0
9
0
9
% R
% Ser:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
9
0
0
0
0
9
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
25
25
25
25
17
0
9
17
9
25
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _